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  • Title: Mutagenicity evaluation of KB-944, a new calcium antagonist, in the Ames bacterial system.
    Author: Tanaka H, Tanaka A, Tsunetoshi Y, Sotomura M, Nose T.
    Journal: Arzneimittelforschung; 1982; 32(9):1087-8. PubMed ID: 6756416.
    Abstract:
    Evaluation of the mutagenic activity of diethyl 4-(benzothiazol-2-yl) benzylphosphonate (KB-944) was performed using bacteria. The method consisted of mutagens or KB-944 with and without metabolic activation, and two bacteria; Salmonella typhimurium 5 test strains, TA 1535, TA 100, TA 1537, TA 1538 and TA 98, and Escherichia coli WP 2 uvr A. Results indicated that KB-944 had no mutagenic activity against S. typhimurium and E. coli.
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