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  • Title: Gene expression in eukaryotes.
    Author: Brown DD.
    Journal: Oncodev Biol Med; 1982; 4(1-2):9-29. PubMed ID: 6757878.
    Abstract:
    Gene expression in eukaryotes is influenced by a wide variety of mechanisms, including the loss, amplification, and rearrangement of genes. Genes are differentially transcribed, and the RNA transcripts are variably utilized. Multigene families regulate the amount, the diversity, and the timing of gene expression. The present level of understanding of gene expression in eukaryotes is attributable mainly to biochemical methods rather than to traditional genetics. The new techniques that permit analysis and modification of purified genes of known function will identify both the control regions in eukaryotic genes and the molecules within cells that influence gene expression.
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