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  • Title: The stimulation by ethanol of rat aorta ring prostacyclin-like synthesis is related to the age of the animal.
    Author: Adolfs MJ, Elliott GR.
    Journal: Agents Actions Suppl; 1982; 11():217-24. PubMed ID: 6758551.
    Abstract:
    Rat aorta rings were incubated with Tris/HCl buffer and the release of prostacyclin-like material (PGI2-L) measured indirectly by assaying the increase in cAMP in rat platelets incubated with the aorta incubation medium. The addition of 1% ethanol to the incubation system stimulated PGI2-L formation. Aorta rings from 16 week old rats synthesised more PGI2-L material than aorta tissue removed from 6 week old animals.
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