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  • Title: Use of single-agent antimicrobial therapy in the treatment of polymicrobial female pelvic infections.
    Author: Faro S, Sanders CV, Aldridge KE.
    Journal: Obstet Gynecol; 1982 Aug; 60(2):232-6. PubMed ID: 6760009.
    Abstract:
    One hundred twenty patients with either postpartum endomyometritis or postgynecologic surgical infections were treated either with ticarcillin, clindamycin, or chloramphenicol. One hundred nine (91%) responded successfully to single-agent antimicrobial therapy. Most of the infections were polymicrobial, involving both aerobic and anaerobic bacteria. Forty patients were treated with ticarcillin, with 90% responding successfully; 48 were treated with chloramphenicol, with 94% responding successfully; and 32 were treated with clindamycin, with 88% responding successfully. Single-agent antimicrobial therapy appears to be appropriate for treating polymicrobial obstetric and gynecologic soft tissue infections.
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