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  • Title: Prenatal ultrasonographic diagnosis of spina bifida: timing of examination.
    Author: Toms D, Brown BS.
    Journal: J Can Assoc Radiol; 1982 Dec; 33(4):276-8. PubMed ID: 6761342.
    Abstract:
    A detailed ultrasonographic examination of the fetal vertebral column may be very close to normal at 16 weeks' gestation, yet may conclusively demonstrate spina bifida four and one-half weeks later, as exemplified in a patient we report. We suggest that if there is any reason to investigate a possible neural tube defect, a detailed ultrasonographic examination of the entire vertebral column should be made at approximately 20 weeks if spina bifida has not been demonstrated earlier.
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