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  • Title: Evidence for the presence of circulating immune complexes in serum and C3b and C3d on red cells of kala-azar patients.
    Author: Kharazmi A, Rezai HR, Fani M, Behforouz NC.
    Journal: Trans R Soc Trop Med Hyg; 1982; 76(6):793-6. PubMed ID: 6761907.
    Abstract:
    The presence of immune complexes in serum, and the existence of immunoglobulin and complement on the surface of red blood cells of kala-azar patients was studied. IgG, C3b and C3d were detected on the surface of red cells of some of the patients by a direct anti-globulin test. PEG precipitation and platelet aggregation techniques demonstrated the existence of immune complexes in the sera of all nine patients examined. Both Leishmania antigen and anti-Leishmania antibody were detected in the PEG-precipitated immune complexes.
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