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Title: Attempts to protect rabbits against challenge with virulent, cell-associated, malignant catarrhal fever virus. Author: Rossiter PB. Journal: Vet Microbiol; 1982 Nov; 7(5):419-25. PubMed ID: 6761953. Abstract: Rabbits hyperimmunized with inactivated malignant catarrhal fever virus (MCFV) infected rabbit lymph node cells did not develop specific antibodies to the virus and succumbed to challenge with live MCFV-infected lymphoid cells. Rabbits hyperimmunized with either inactivated or live, cultured bovine kidney cells infected with MCFV developed antibodies to the virus, but also succumbed to challenge with live MCFV-infected rabbit lymphoid cells. Rabbits hyperimmunized with live cultured rabbit kidney cells infected with MCFV developed antibodies to the virus and resisted challenge with live MCFV-infected rabbit lymphoid tissues 47 weeks later. However, rechallenge of this group at 90 weeks post immunization resulted in the death of 2/4 rabbits suggesting a waning immunity.[Abstract] [Full Text] [Related] [New Search]