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  • Title: [Role of catecholaminergic mechanisms of the brain in fixation of temporary connections].
    Author: Orlova NV.
    Journal: Zh Vyssh Nerv Deiat Im I P Pavlova; 1978; 28(3):538-41. PubMed ID: 676501.
    Abstract:
    A comparison was made betseen the influence of administering disulfiram and L-Dopa on retention of defensive and drinking conditioned reflexes in rats. A great drop of noradrenaline content in the brain while worsening the elaboration of defensive conditioned reflexes, does not prevent their fixation as well as fixation of drinking conditioned reflexes elaborated in one pairing. Increased catecholamine content after administration of L-Dopa does not affect the elaboration of defensive and the fixation of defensive and drinking conditioned reflexes. Interference in the activity of the brain catecholaminergic mechanisms does not directly affect the fixation of temporary connections, regardless of the emotional sign of reinforcement used in their elaboration.
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