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  • Title: Ceruletide-assisted examination of the small bowel.
    Author: Robbins AH, Wetzner SM, Landy MD.
    Journal: AJR Am J Roentgenol; 1980 Feb; 134(2):343-7. PubMed ID: 6766244.
    Abstract:
    Ceruletide, a decapeptide similar in action to cholecystokinin, was studied in a randomized fashion in 48 patients undergoing routine small bowel examination. Parenteral administration of Ceruletide demonstrated a significantly decreased small bowel transit time (28.8 min) when compared with placebo (67 min) (P less than 0.005). However, this was offset by a diminution in anatomic quality particularly in the distal ileum. A hypotonic action on the duodenual bulb and sweep was observed in 77% of patients after the administration of Ceruletide. This hypotonic effect may prove to be a useful adjunct in the performance of an upper gastrointestinal series.
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