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  • Title: Combined gentamicin-tobramycin-corticosteroid treatment. II. Effect on gentamicin-resistant Pseudomonas keratitis.
    Author: Smolin G, Okumoto M, Leong-Sit L.
    Journal: Arch Ophthalmol; 1980 Mar; 98(3):473-4. PubMed ID: 6767466.
    Abstract:
    In an experimental model of Pseudomonas keratitis produced by a gentamicin sulfate-resistant, tobramycin sulfate-sensitive strain of P aeruginosa, the results of two treatment regimens-(1) with gentamicin and tobramycin alone and (2) with gentamicin, tobramycin, and a steroid-were evaluated. All of the animals exhibited ultimately the same amount of corneal inflammation and corneal scarring. In the group receiving the antibiotic-steroid combination, the corneal lesions healed more slowly.
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