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  • Title: Solubility of carbon dioxide in lipid bilayer membranes and organic solvents.
    Author: Simon SA, Gutknecht J.
    Journal: Biochim Biophys Acta; 1980 Mar 13; 596(3):352-8. PubMed ID: 6767496.
    Abstract:
    Partition coefficients of carbon dioxide into lipid bilayers (liposomes) and organic solvents were measured as a function of temperature. The molar partition coefficient of CO2 into liposomes of egg lecithin at 25 degrees C was 0.95 (ml CO2/ml lipid)/(ml CO2/ml saline). The addition of an equimolar amount of cholesterol to the egg lecithin decreased the partition coefficient by about 25%. The partition coefficients for CO2 into liposomes at 25 degrees C were lower than the partition coefficients into octanol (1.3), hexadecane (1.5) and olive oil (1.7). The results are discussed in terms of the solubility-diffusion model of non-electrolyte transport through lipid bilayer membranes.
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