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  • Title: [Age differences in the hormonal reaction of the adrenals and testes to stress exposure in monkeys].
    Author: Butnev VIu, Lomaia LP, Taranov AG, Goncharov NP.
    Journal: Biull Eksp Biol Med; 1980 Feb; 89(2):157-60. PubMed ID: 6768408.
    Abstract:
    Function of the adrenals and testes in immature and adult male baboons was studied in immobilization stress conditions. Concentrations of testosterone, 5d-dihydrotestosterone, hydrocortisone and precursors (progesterone, pregnenolone, 17-hydroxyprogesterone, 17-hydroxypregnenolone and 11-deoxycortisol) were determined in peripheral blood plasma by radioimmunoassay. It was shown that the main age-specific differences in hormonal reaction to stress are an unchanged level of androgens in the blood of immature animals and less marked increase in the level of hydrocortisone as compared to adult monkeys. The content of steroid precursors in the blood of immature monkeys diminished significantly in stressful conditions while in adult monkeys the level of the precursors was 3-5 times as increased.
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