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  • Title: [Transplantation of the islands of Langerhans: evaluation and perspectives].
    Author: Mosimann F.
    Journal: Schweiz Med Wochenschr; 1980 Apr 12; 110(15):550-5. PubMed ID: 6769153.
    Abstract:
    Islets of Langerhans transplantation was studied in four groups of dogs (autotransplantation after immediate or delayed total pancreatectomy; allotransplantation with immediate total pancreatectomy or 4 days after total pancreatectomy). It is concluded: 1. that it is unnecessary to separate endocrine from exocrine pancreatic elements; 2. that a moderate hyperglycemia for a few days after transplantation is required for ultimate survival and function of transplanted material; 3. that further experimental work has to be done before allotransplantation can be safely performed in man.
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