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  • Title: Haemoglobin D Los Angeles, D-beta +-thalassaemia, and D-beta o-thalassaemia. A report of two Canadian families.
    Author: Wong SC, Ali MA.
    Journal: Acta Haematol; 1980; 63(3):151-5. PubMed ID: 6769280.
    Abstract:
    The first 2 Canadian cases of combinations of Hb D Los Angeles and beta-thalassaemia were found in an Italian family and an East Indian family in Hamilton, Ont. The structure of the Hb D variant was identified by radioimmunoassay. The beta +-thalassaemia trait in the Italian family and the beta o-thalassaemia trait in the East Indian family were confirmed by studies of globin chain synthesis. Previous cases of Hb D-beta-thalassaemia were summarized and family studies of the 2 new cases were presented.
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