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  • Title: Interlaboratory comparison of serum vitamin B12 assay.
    Author: Mollin DL, Hoffbrand AV, Ward PG, Lewis SM.
    Journal: J Clin Pathol; 1980 Mar; 33(3):243-8. PubMed ID: 6769970.
    Abstract:
    The results have been compared of microbiological and radioisotope dilution (RID) assay of serum vitamin B12 by participants in national interlaboratory trials in Britain. There was wide variation between the individual participants, especially marked in the L. leichmannii microbiological assay and in the RID methods, whereas excellent correlation, reproducibility, and recovery were obtained in reference laboratories by microbiological assay with both E. gracilis and L. leichmannii. In general, RID gave higher results than microbiological assay. The need for suitable reference sera is emphasised.
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