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  • Title: Prostaglandin synthetase activity in vascular tissue of male and female rats.
    Author: Maggi FM, Tyrrell N, Maddox Y, Watkins W, Ramey ER, Ramwell PW.
    Journal: Prostaglandins; 1980 Jun; 19(6):985-93. PubMed ID: 6770422.
    Abstract:
    1. Isolated perfused lungs from mature male rats show greater conversion of 14C Arachidonic Acid to cyclo-oxygenase products than females. 2. Following unlabelled arachidonate infusion, the male lungs release more 6-K-PGF1 alpha and TxB2 than females. 3. Aortic rings from male rats release more PGI2-like material and 6-K-PGF1 alpha than the females. 4. These data indicate an elevated PG synthetase activity in male rats as compared with females.
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