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  • Title: Ribonucleotide reductase activity in vitamin B12-deficient Euglena gracilis.
    Author: Carell EF, Seeger JW.
    Journal: Biochem J; 1980 May 15; 188(2):573-6. PubMed ID: 6772171.
    Abstract:
    The ribonucleotide reductase activities in vitamin B12-sufficient and -deficient cells of Euglena gracilis were measured. We found that the cells progress into vitamin B12 deficiency the enzyme activity increases, reaching a maximum value of 20-fold in advanced deficiency. No signigicant differences in the activities were found to result as a consequence of different growth conditions. We propose that the increased activity in vitamin B12-deficient cells is due to an increase in enzyme protein.
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