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  • Title: Turnover of proteins in asporogenic Bacillus megaterium. Evidence for a gradual decrease of the turnover rate.
    Author: Váchová-Philippová L, Strnadová M, Chaloupka J.
    Journal: Folia Microbiol (Praha); 1980; 25(3):185-90. PubMed ID: 6772528.
    Abstract:
    The rate of protein turnover in asporogenic Bacillus megaterium decreases continuously during incubation in a sporulation medium. The capability of equilibration of external amino acids with amino acids in the metabolic pool of non-growing cells was retained for at least 5 h. Leucine, while repressing the synthesis of the exocellular protease, does not significantly influence the course of protein degradation in vivo. Transfer of non-growing cells after 4 h to a fresh sporulation medium does not influence the rate of protein degradation. The gradual decrease of the rate of protein turnover in non-growing cells of the asporogenic variant is thus not an artifact caused by a decreased uptake of amino acids by cells or by conditions under which the protein turnover is determined.
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