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  • Title: In vivo characteristics of thaw siphon cryoprecipitate compared to other factor VIII preparations.
    Author: Toolis F, McKay G, Prowse CV.
    Journal: Thromb Haemost; 1980 Feb 29; 43(1):25-7. PubMed ID: 6773169.
    Abstract:
    5 severe haemophiliacs were infused with cryoprecipitate prepared by the continuous thaw-siphon technique, with cryoprecipitate prepared by overnight thawing and with intermediate-purity factor VIII concentrate. All 3 preparations gave a similar mean half-life for coagulant factor VIII of approximately 10 hours. The immediate recovery of this activity was similar for the 2 cryoprecipitates, but higher for the purified concentrate.
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