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  • Title: An immunoglobulin deletion mutant with implications for the heavy-chain switch and RNA splicing.
    Author: Dunnick W, Rabbitts TH, Milstein C.
    Journal: Nature; 1980 Aug 14; 286(5774):669-75. PubMed ID: 6774257.
    Abstract:
    The IF2 immunoglobulin mutant is a DNA deletion of one coding segment and large sections of the flanking intervening sequences. The deletion results in a new splicing pattern and starts in a DNA region containing tandemly repeated sequences which may carry heavy-chain class switch signals.
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