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  • Title: High-mannose glycopeptides from embryonal carcinoma cells.
    Author: Muramatsu T, Gachelin G, Jacob F.
    Journal: J Biochem; 1980 Sep; 88(3):685-8. PubMed ID: 6774975.
    Abstract:
    Endo-beta-N-acetylglucosaminidase H released four major oligosaccharides from high-mannose glycopeptides prepared from embryonal carcinoma cells. The oligosacchaides were indistinguishable from (Man)9GlcNAc, (Man)8GlcNAc, (Man)7GlcNAc, and (Man)6GlcNAc isolated from fibroblasts. This result suggests that the biosynthetic pathway of asparagine-linked oligosaccharides in early embryonic cells is controlled as in adult cells, at least to the initial stage of processing of the nascent oligosaccharide transferred from lipid-linked intermediate.
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