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  • Title: Immunoradiometric assay of procoagulant factor VIII antigen (VIIICAG).
    Author: Muller HP, van Tilburg NH, Bertina RM, Terwiel JP, Veltkamp JJ.
    Journal: Clin Chim Acta; 1980 Oct 23; 107(1-2):11-9. PubMed ID: 6775848.
    Abstract:
    An immunoradiometric assay of procoagulant factor VIII antigen was developed using a human antibody to the procoagulant activity of factor VIII (VIII:C). The assay measures specifically the antigen related to factor VIII procoagulant activity (VIIICAG) both in plasma and in serum. VIII:C and VIIICAG were measured in a group of healthy individuals and in a group of haemophilia A patients. In haemophilia A at least four groups can be recognised on the basis of the presence or absence of VIII:C and VIIICAG and the VIII:C/VIIICAG ratio.
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