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  • Title: Hemolytic complement levels of neonatal calves delivered from protein-energy malnourished dams and subjected to cold stress.
    Author: Woodard LF, Eckblad WP, Olson DP, Bull RC, Everson DO.
    Journal: Cornell Vet; 1980 Jul; 70(3):266-71. PubMed ID: 6775871.
    Abstract:
    Beef cows were placed on protein-deficient and/or energy deficient rations for the last 150 days of pregnancy. After birth their calves were placed on 1 or 21 C environmental chambers for 3 days, and sera were collected for determination of complement (C) levels. At birth, the mean complement hemolytic (CH50) titer of all calves was 46.0 +/- 1.7 units, but the titer rapidly dropped (P < 0.01) to 31.6 +/- 1.2 by 12 hours after birth. Levels of C activity then began to rise and reached a mean titer of 76.3 +/- 3.0 by 3 days of age. A quadratic curve of predicted CH50 values was constructed from the data. Differences between principal and control groups of calves were not detected. These results suggest that maternal protein-calorie deprivation and limited cold stresses have little effect on levels of C activity in the bovine neonate. Possible explanations for the decrease in CH50 levels after birth are discussed.
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