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Title: Radiation dose from human platelets labelled with indium 111. Author: van Reenen OR, Lötter MG, Minnaar PC, Heyns Adu P, Badenhorst PN, Pieters H. Journal: Br J Radiol; 1980 Aug; 53(632):790-5. PubMed ID: 6777011. Abstract: The biological distribution of 111In-labelled platelets in normal subjects was determined by whole-body counting and scintillation-camera computer-assisted imaging. Using these data, organ radiation dose was quantitated. The highest radiation dose of 7.4 mGy/MBq (27.4 rad/mCi) was received by the spleen and 0.97 mGy/MBq (3.6 rad/mCi) by the liver. While body radiation dose was 0.25 mGy/MBq (0.9 rad/mCi). The gonad radiation dose of males was 0.14 mGy/MBq (0.5 rad/mCi) and that of females 0.22 mGy/MBq (0.8 rad/mCi). These estimates indicate that radiation doses received from 8.6 MBq of 111In-labelled platelets are well within acceptable limits, and that 111In is a safe labelling agent for the study of platelet kinetics.[Abstract] [Full Text] [Related] [New Search]