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  • Title: [Level of polysomes in cells of Escherichia coli treated with sublethal doses of aminoglycosides].
    Author: Cortay JC, Marchal J, Cozzone A.
    Journal: C R Seances Acad Sci D; 1980 Oct 06; 291(5):473-6. PubMed ID: 6777066.
    Abstract:
    Polysome level was measured in Escherichia coli cells grown in the presence of sublethal doses of four different aminoglycosides which all induce mistranslation: streptomycin, neomycin, kanamycin and gentamycin. No significant variation was noticed as referred to the level of polysomes in normally growing cells. This observation indicates that the erroneous incorporation of amino acids into polypeptide chains does not necessarily result in the release of ribosomes from messenger RNA molecules.
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