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  • Title: [Method of partitioning polyene macrolide antibiotics].
    Author: Golubeva LA, Kashkin AP, Shenin IuD, Malkov MA, Larkin AI.
    Journal: Antibiotiki; 1978 Jun; 23(6):503-6. PubMed ID: 677835.
    Abstract:
    Levorin and mycoheptin, polyenic antibiotics were separated into 3 and 7 heptaenic components respectively by the method of disc electrophoresis in 7.5 per cent polyacryl amide gel prepared with tris-HCl buffer, pH 8.9. It was shown that nystatin had different composition as dependent on the organism producing it. The results of electrophoresis confirmed the data of the counter-current distribution.
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