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  • Title: The kinetics of haemopoietic differentiation assessed by in vitro bone marrow culture in endotoxin-treated and in anaemic calves.
    Author: Kaaya GP, Maxie MG.
    Journal: Res Vet Sci; 1980 Jul; 29(1):63-7. PubMed ID: 6779359.
    Abstract:
    Marrow aspirates from calves injected with Pseudomonas aeruginosa endotoxin showed an increased number of granulocyte/macrophage progenitor cells, and a reduced number of erythroid progenitor cells. On the other hand, marrow aspirates from calves made anaemic by repeated phlebotomy showed an increased number of erythroid progenitor cells, and a reduced number of granulocyte/macrophage progenitor cells. These observations were interpreted as evidence of stem cell erythroid-granuloid directional competition occurring in response to the need for a particular cell type.
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