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  • Title: The use of anesthetic drugs to reduce ICP changes in head-injured patients.
    Author: Moss E, Gibson JS, McDowall DG.
    Journal: Acta Anaesthesiol Belg; 1980; 31 Suppl():43-8. PubMed ID: 6779498.
    Abstract:
    Chest physiotherapy causes increases in intracranial pressure (ICP) in patients with severe head injuries. In mechanically hyperventilated severe head injuries (PaCO2 3.3 - 4 kPa) 50% nitrous oxide in 50% oxygen exacerbated ICP increases associated with chest physiotherapy, while thiopentone and Althesin reduced these changes in ICP.
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