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  • Title: Effects of prostaglandins on avidin induction in the chick oviduct.
    Author: Heinonen PK.
    Journal: Arch Int Pharmacodyn Ther; 1978 Apr; 232(2):211-6. PubMed ID: 677958.
    Abstract:
    Effects of exogenous prostaglandins (PGs) on avidin synthesis in the oviduct were studied in immature diethylstilboestrol-treated chicks. Among eight tested PGs only PGF-2alpha was effective when injected directly into the oviduct, but intraperitoneal and intravenous administration also caused avidin induction. 1 ng of PGF-2alpha/100 g B.W. injected into the oviduct caused avidin synthesis. The effect of PGF-2alpha on avidin induction occurred as early as 3 hr after intraoviductal administration. This study provides an additional evidence for the hypothesis that PGF-2alpha may be involved in the mechanism of avidin induction in the chick oviduct.
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