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  • Title: Small-intestine involvement in Waldenstrom's macroglobulinemia. Case report and review of the literature.
    Author: Brandt LJ, Davidoff A, Bernstein LH, Biempica L, Rindfleisch B, Goldstein ML.
    Journal: Dig Dis Sci; 1981 Feb; 26(2):174-80. PubMed ID: 6780283.
    Abstract:
    A patient presented with a three-year history of diarrhea and was found to have a monoclonal gammopathy (IgM lambda) and a malabsorption syndrome with dilatation of the small bowel. Small-intestinal biopsy revealed a homogeneous eosinophilic granular material between the epithelial cells. On electron microscopy this material was shown to consist of an electron-opaque background mixed wit radiolucent lipid sheres. Immunofluorescent studies showed the accellular material to consist entirely of IgM-reactive material. The patient's course and a review of the literature is presented.
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