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  • Title: [Average time prognosis of hypertension in qualitatively different treatment protocols].
    Author: Knappe J, Dück KD, Strube G, Holtz H, Heinrich J.
    Journal: Z Gesamte Inn Med; 1980 Nov 01; 35(21):suppl 136-8. PubMed ID: 6781157.
    Abstract:
    In 1969 within pilot studies in an Erfurt district altogether 254 patients with definitive hypertension as well as 208 patients with borderline hypertension of the male age groups from 1914 to 1923 were recognized. 135 test persons with definitive hypertension (RR--160/95 Torr) were treated antihypertensively within a clinical and ambulatory preventive programme for 8 years and compared with a control group of the same age (119 males of 45-54 years) concerning the presence of possible complications of hypertension, which was treated with unsatisfactory results. By a strict, permanently normotensive decrease of blood pressure--as pharmacotherapy above all the beta-receptor blocker propranolol alone or in the approved combination therapy with dihydralazine and/or hydrochlorothiazide was used--in connection with suitable measures for the intervention of other individual factors with effect on heart and circulation the risk of complications in definitive hypertension could be reduced. Taking into consideration the own long-term observations the necessity of a possibly early beginning medicamentous, antihypertensive permanent therapy of hypertension is without doubt, in borderline hypertension, however, it still remains actual subject of the discussion.
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