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Title: Structural prediction of sugar-binding proteins functional in chemotaxis and transport. Author: Argos P, Mahoney WC, Hermodson MA, Hanei M. Journal: J Biol Chem; 1981 May 10; 256(9):4357-61. PubMed ID: 6783660. Abstract: Comparisons of the D-galactose- and D-ribose-binding protein amino acid sequences and secondary structure predictions with the known primary and three-dimensional structure of L-arabinose-binding protein suggest that the three proteins have similar molecular structures. These studies also indicate an evolutionary relationship among the proteins. One region of striking homology between the galactose- and ribose-binding proteins suggests that this may be th protein-protein contact site for interaction with the membrane-bound chemotaxis receptor. The ligands and the geometry of the galactose binding site are also predicted.[Abstract] [Full Text] [Related] [New Search]