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Title: Dopamine inhibits the naloxone induced gonadotrophin rise in man. Author: Delitala G, Devilla L, Di Biaso D. Journal: Clin Endocrinol (Oxf); 1980 Nov; 13(5):515-8. PubMed ID: 6784978. Abstract: Twenty milligrams of the opiate receptor antagonist naloxone were infused over 3 h to five young male volunteers. Naloxone produced a significant rise in both LH and FSH, but did not affect serum prolactin levels. The infusion of dopamine (4 microgram . kg-1 . min-1) completely abolished the naloxone effect on gonadotrophin release. The results suggest a possible interaction between dopamine, opioid receptors and gonadotrophin secretion in man.[Abstract] [Full Text] [Related] [New Search]