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  • Title: Metabolism of [14C] terbutryn (2-(t-butylamino)-4-(ethylamino)-6-(methylthio-s-triazine) by rats and goat.
    Author: Larsen GL, Bakke JE, Feil VJ.
    Journal: Biomed Mass Spectrom; 1978 Jun; 5(6):382-900. PubMed ID: 678607.
    Abstract:
    Sixteen metabolites of terbutryn were isolated from the urine and feces of either rats or a goat given single oral doses of terbutryn-[14C](2-(t-butylamino)-4-(ethylamino)-6-(methylthio)-s-triazine). The metabolites resulted from one or more of the following changes: S-demethylation, conversion of the methylthio group to a hydroxy group; N-deethylation; oxidation of the terminal carbon of the ethyl group to a carboxylic acid; oxidation of a terminal carbon of the t-butyl group to either an alcohol or a carboxylic acid; or conjugation with glucuronic acid.
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