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  • Title: Antihypertensive effect of plasma volume expansion in pregnancy-associated hypertension.
    Author: Gallery ED, Delprado W, Györy AZ.
    Journal: Aust N Z J Med; 1981 Feb; 11(1):20-4. PubMed ID: 6788033.
    Abstract:
    Plasma and total extracellular fluid volume expansion was confirmed in normal pregnant women in the third trimester of pregnancy. The plasma volume contraction of pregnancy-associated hypertension (pre-eclampsia) was found to be associated with an increase in the interstitial compartment of extracellular fluid volume. The infusion of a plasma volume expander produced significant amelioration of hypertension for 48 h associated with partial reversal of the disturbance of fluid distribution. This finding confirms the central place of volume contraction in maintenance of elevated blood pressure in pregnancy-associated hypertension.
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