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  • Title: [Improvement of post-training performance 4 weeks after stimulation of the locus coeruleus in rats : absence of an effect of a lesion of the dorsal noradrenergic bundle].
    Author: Velley L, Cardo B, Kempf E.
    Journal: C R Seances Acad Sci III; 1981 May 04; 292(16):943-6. PubMed ID: 6790192.
    Abstract:
    The dorsal noradrenergic bundle of 25 day old rats was lesioned by means of a local injection of 6-hydroxydopamine. Eight days later each locus coeruleus was stimulated for 4 hrs. Four weeks later the animals were tested on the acquisition of food-reinforced operant task. Not lesioned but stimulated, lesioned but not stimulated and not lesioned not stimulated rats were used in controls. The locus coeruleus stimulation induced nearly the same improvement of performances whether or not the dorsal noradrenergic bundle was lesioned.
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