These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Comparative haemodynamic and metabolic effects of vasodilator and inotropic agents in experimental myocardial infarction.
    Author: Franciosa JA, Notargiacomo AV, Cohn JN.
    Journal: Cardiovasc Res; 1978 May; 12(5):294-302. PubMed ID: 679229.
    Abstract:
    Following coronary embolisation and onset of left ventricular failure 27 awake dogs were randomly assigned to infusion of saline (controls), nitroprusside, or dobutamine (a new inotropic agent). Nitroprusside and dobutamine both increased cardiac output and lowered left ventricular filling pressure while raising coronary sinus flow. Dobutamine, however, increased myocardial oxygen consumption whereas nitroprusside reduced it. Therefore vasidilators may be more beneficial than inotropic agents in acute myocardial infarction.
    [Abstract] [Full Text] [Related] [New Search]