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  • Title: [The Stein-Leventhal syndrome. Clinical, biological and anatomic study of 6 cases in adolescent girls (author's transl)].
    Author: Petrus M, Claverie J, Vancina S, Becue J, Dutau G, Rochiccioli P.
    Journal: Arch Fr Pediatr; 1981; 38(6):417-22. PubMed ID: 6794535.
    Abstract:
    Clinical, biological and anatomic studies were performed in 6 adolescent girls with the Stein-Leventhal syndrome. The rare occurrence of this syndrome in pediatrics is emphasized. The main clinical signs consist of obesity, hirsutism and menstrual irregularities. Basic LH and plasma testosterone are useful diagnostic means, as well as -- in children -- the suppression-stimulation and LH-RH tests. However, coelioscopy is necessary to allow a correct diagnosis. Histological examination might not be absolutely necessary since a large biopsy could be responsible for untimely ovulation. Estrogens and anti-androgens are the only logical treatment at the time of puberty.
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