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  • Title: Chemoprevention of mammary tumorigenesis by a combined regimen of selenium and vitamin A.
    Author: Ip C, Ip MM.
    Journal: Carcinogenesis; 1981; 2(9):915-8. PubMed ID: 6794926.
    Abstract:
    Mammary tumorigenesis induced in rats by 7,12-dimethylbenz[a]anthracene was markedly suppressed by combined dietary supplementation with sodium selenite and retinyl acetate; final tumor yield was reduced to 8% of control as compared with 51% and 36%, respectively, for selenium and retinyl acetate alone. A continuous intake of both agents was necessary to sustain the chemopreventive effect.
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