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  • Title: Deoxyribonucleic acid methylation in mycobacteria.
    Author: Srivastava R, Gopinathan KP, Ramakrishnan T.
    Journal: J Bacteriol; 1981 Nov; 148(2):716-9. PubMed ID: 6795184.
    Abstract:
    Deoxyribonucleic acid modification in six strains of mycobacteria was investigated. The presence of 5-methylcytosine in the virulent strain Mycobacterium tuberculosis H37Rv and its absence in the avirulent strain M. tuberculosis H37Ra and other saprophytic, fast-growing mycobacteria appear to be the salient features. However, deoxyribonucleic acid from M. smegmatis SN2 lysogenized with the temperature phage I3 showed the presence of 5-methylcytosine. All of the strains had N6-methyladenine.
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