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  • Title: [Comparison of conventional renal clearance values with differently evaluated results of radioisotope nephrography (author's transl)].
    Author: Grebe SF, Weise M, Berghäuser H, Fängewisch GL, Temme H.
    Journal: Radiologe; 1981 Dec; 21(12):553-61. PubMed ID: 6796996.
    Abstract:
    81 patients with renal abnormalities or renal disorders of different genesis and severity with and without restricted renal function were investigated by means of the classical PAH- and inulin-clearance. Furthermore a radioisotope nephrography was carried out after application of I 131-Hippuran followed by Cr 51-EDTA. In addition the activity reduction was measured above the shoulder, as well as the activity in serum samples and urine samples gained 30 min after application. A comparison of the clearance values found with those of conventional clearance resulted in poor correlation for I 131-Hippuran (r = 0.54) and no correlation for Cr51-EDTA. Of the many parameters of the radioisotope nephrogram curves only the following are able to give sufficient quantitative functional results: The parameters connected with the rise of the curve between the 48rh and 120rh s and those connected with the slope of the secant. This is also true for the values of activity measured in the urine.
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