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  • Title: Effect of LH and FSH on testosterone release from cultured Leydig cells.
    Author: Bilińska B, Szołtys M.
    Journal: Endocrinol Exp; 1981 Dec; 15(4):251-7. PubMed ID: 6797812.
    Abstract:
    The level of testosterone in incubation media of cultures of Leydig cells isolated from mouse testes were measured by specific radioimmunoassay. Luteinizing hormone (LH) in a concentration of 10, 100 and 500 ng per 1 ml of culture medium stimulated the secretion of testosterone very markedly especially after 2 days of culture. LH in the amount of 100 ng ml-1 exerted the most stimulating effect on testosterone production by cultured Leydig cells. Follicle stimulating hormone (FSH) in a concentration 100 ng ml-1 of culture medium did not influence significantly the androgen production.
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