These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Electron microscopic and cytochemical observations of theophylline and melanocyte-stimulating hormone effects on melanoma cells in culture.
    Author: Hu F, Mah K, Teramura DJ.
    Journal: Cancer Res; 1982 Jul; 42(7):2786-91. PubMed ID: 6805946.
    Abstract:
    The effects of theophylline and melanocyte-stimulating hormone on B16 melanoma cells in culture cells were studied by electron microscopy and dopa cytochemistry. The data show that theophylline and melanocyte-stimulating hormone enhance melanogenesis by activating tyrosinase synthesis and its transfer but that neither affects the synthesis of the well-organized eumelanosome matrix. Their pigmenting effects appear to be limited to the melanogenic cells and result from a marked increase, particularly in theophylline-treated cells, in pheomelanosome formation.
    [Abstract] [Full Text] [Related] [New Search]