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  • Title: [Long-term treatment and prevention of uric acid urolithiasis with allopurinol].
    Author: Jarrar K.
    Journal: Fortschr Med; 1982 May 27; 100(20):967-8. PubMed ID: 6807789.
    Abstract:
    29 patients (20 male and 9 female, average age 55 years), suffering from uric acid-urolithiasis were treated with Zyloric-U over a period of 8 to 20 months. Two of them had side effects (cutaneous symptoms). In all other cases the stones were dissolved or diminuated. Chemical analysis demonstrated a significant reduction of serum uric acid as well as a decrease of calcium secretion in the urine. Yet the urine-pH of 5 remained unchanged. In some cases, if the patients excreted gravel and if the level of uric acid was not lowered sufficiently the dose was raised to twice 300 mg. A report of the follow-up of these patients shall be published later.
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