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  • Title: Severe congenital hypoglossia and micrognathia with other multiple birth defects.
    Author: Oulis CJ, Thornton JB.
    Journal: J Oral Pathol; 1982 Aug; 11(4):276-82. PubMed ID: 6809915.
    Abstract:
    Severe congenital hypoglossia with the anterior two-thirds of the tongue missing is a rare finding. This case report describes an infant 14 months of age who manifests this tongue anomaly along with other congenital malformations including an underdeveloped mandible, partial anodontia, enamel hypoplasia, situs inversus, dextrocardia, and asplenia. Only one other case similar to this case has been reported in the literature. There is no report of any case of severe congenital hypoglossia with asplenia. The etiology of this birth defect is only speculative at this time, but the mother of our patient was exposed to radiation from routine chest films during her first trimester of pregnancy.
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