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  • Title: [Artificial respiration in cerebral resuscitation].
    Author: Chiolero R.
    Journal: Schweiz Med Wochenschr; 1982 Jul 06; 112(27-28):963-6. PubMed ID: 6810454.
    Abstract:
    CO2 is a potent cerebral vasodilator which induces major changes in cerebral blood flow and volume. Acute hypocapnia decreases cerebral blood volume; thus the intracranial pressure can be reduced rapidly, thereby improving cerebral hemodynamics. Hypocapnia, rapidly achieved by controlled hyperventilation, is therefore a valid treatment in cerebral resuscitation, especially when associated with elevated intracranial pressure. However, the effect of hypocapnia is short and unusually does not exceed a few hours. Consequently the indications for prolonged hyperventilation are very limited, if they exist at all. Intracranial pressure and cerebral blood flow changes induced by PEEP are still controversial.
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