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  • Title: [The TRH test in latent thyroid pathology].
    Author: De Remigis P, Damiani A, Vianale L, D'Angelo M, Bonaduce S, Della Loggia F, Basilico L, Sensi S.
    Journal: Boll Soc Ital Biol Sper; 1982 Jun 15; 58(11):663-5. PubMed ID: 6810907.
    Abstract:
    TRH-test is an usefull tool for diagnostic purpose in thyroid disease. We challenged with TRH 4 groups of patients (1 degrees non toxic diffuse goitre, 2 degrees nodular goitre (Plummer's disease), 3 degrees euthyroid ophthalmic Graves' disease, 4 degrees hemithyroidectomy) with different thyroid affections who showed no symptoms and presented normal values of total thyroid hormones, in comparison with a control group. These groups displayed normal and pathological (blunted or absent and exaggerated) responses of TSH to TRH. Therefore TRH-test ra presents a good mean to recognize subclinical forms both hyperthyroidism and hypothyroidism.
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