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  • Title: The presence of 7-hydroxychlorpromazine in CSF of chloropromazine-treated patients.
    Author: Alfredsson G, Lindberg M, Sedvall G.
    Journal: Psychopharmacology (Berl); 1982; 77(4):376-8. PubMed ID: 6813900.
    Abstract:
    7-Hydroxychlorpromazine (7-OHCPZ) has been identified and quantified in CSF from chlorpromazine (CPZ)-treated schizophrenic patients. The level of the metabolite in CSF was similar to that of CPZ. In serum the amount of 7-OHCPZ was about 30% of CPZ. The concentration of 7-OHCPZ in csf was positively and significantly correlated to the serum level.
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