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  • Title: A comparison of phenytoin and pheneturide in patients with epilepsy: a double-blind cross-over trial.
    Author: Gibberd FB, Park DM, Scott G, Gawel MJ, Fry DE, Page NG, Engler C, English JR, Rose FC.
    Journal: J Neurol Neurosurg Psychiatry; 1982 Dec; 45(12):1113-8. PubMed ID: 6819339.
    Abstract:
    A double-blind cross-over trial between pheneturide and phenytoin in ninety-four outpatients with epilepsy is described. There was no significant difference between the frequency of seizures in the two groups. The difficulties in comparing two anticonvulsants of similar efficacy are discussed particularly in relation to ethical problems, the selection of patients and trial design.
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