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  • Title: Histocompatibility antigens (HLA) in multiple sclerosis in Iran.
    Author: Lotfi J, Nikbin B, Derakhshan I, Aghai Z, Ala F.
    Journal: J Neurol Neurosurg Psychiatry; 1978 Aug; 41(8):699-701. PubMed ID: 681957.
    Abstract:
    Thirty-five patients (19 male and 16 female) with clinically definite multiple sclerosis and 100 healthy control subjects were studied for the A and B locus of the HLA system. A significant increase of HLA A3 and A11 of the A locus and B7 of the B locus was observed in patients with multiple sclerosis compared with controls. An increase of antigen A3 was also observed in eight cases of probable multiple sclerosis. A significant increase of both A3 and B7 was observed in patients with multiple sclerosis.
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